induces apoptosis — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7008	Vacquinol-1	Vacquinol 1	JNK
	Vacquinol-1 is an MKK4 activator, which rapidly and selectively induces glioma cell death.		JNK
T35329L	EAD1 TFA(1644388-26-0 Free base)	EAD1 HCL(1644388-26-0 Free base)	Apoptosis , Autophagy
	EAD1 HCL is a potent autophagy inhibitor with antiproliferative activity in lung and pancreatic cancer cells. EAD1 HCL also induces apoptosis		Apoptosis , Autophagy
T20543	Flurochloridone	R 40244,R-40244,R40244,EPA Pesticide Chemical Code 128401	Apoptosis , Reactive Oxygen Species
	Flurochloridone (R 40244) is a selective herbicide. Flurochloridone induces apoptosis and is regulated by mitochondrial dysfunction and oxidative stresses.		Apoptosis , Reactive Oxygen Species
T8978	DD1	3,3'-Diamino-4'-methoxyflavone,HUN85111	Proteasome
	DD1 (HUN85111) is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.		Proteasome
TN1013	Cucurbitacin D		IL Receptor , JNK , STAT
	Cucurbitacin D has anticancer effects, it induces apoptosis through caspase-3 and phosphorylation of JNK in hepatocellular carcinoma cells.		IL Receptor , JNK , STAT
T25049	Allethrin		BCL , Caspase
	Allethrin induces oxidative stress, apoptosis and calcium release. Allethrin, a pyrethroid insecticide is a major mosquito repellent agent.		BCL , Caspase
T10343	AOH1160	N-(2-Oxo-2-(2-phenoxyphenylamino)ethyl)-1-naphthamide	Apoptosis , DNA/RNA Synthesis
	AOH1160 is an inhibitor of proliferating cell nuclear antigen (PCNA). AOH1160 induces apoptosis and causes cell-cycle arrest by interfering with DNA replication.		Apoptosis , DNA/RNA Synthesis
T5352	GLYCODEOXYCHOLIC ACID		Others , Endogenous Metabolite
	Glycodeoxycholic Acid is a bile acid that induces severe pancreatitis in rats. It can induce the apoptosis of SMMC-7721 cells.		Others , Endogenous Metabolite
T23512	VU 0364739 hydrochloride	VU 0364739 HCl	Apoptosis , Phospholipase
	VU 0364739 hydrochloride (VU 0364739 HCl) is a selective and potent inhibitor of phospholipase D2 (PLD2) with IC50s of 20 and 1500 nM for PLD2 and PLD1, respectively.VU 0364739 hydrochloride exhibits potential anticancer...		Apoptosis , Phospholipase
T27138	Declopramide	OXI-104,IMO-B,3-Chloroprocainamide	Apoptosis
	Declopramide (OXI-104) is a novel chemosensitizer with antitumor activity that induces apoptosis and can be used to study colorectal cancer and inflammatory bowel disease.		Apoptosis
T41288	Myristoleic acid	cis-9-tetradecenoic acid,9-Tetradecenoic acid,(Z)-Tetradec-9-enoic acid	Apoptosis
	Myristoleic acid (9-Tetradecenoic acid) is a cytotoxic component in the extract from Serenoa repens. Myristoleic acid induces apoptosis and necrosis in human prostatic LNCaP cells.		Apoptosis
T27579	ICL-CCIC-0019	ICL CCIC 0019	AChR
	ICL-CCIC-0019 is an inhibitor of choline kinase alpha (ChoKα). ICL-CCIC-0019 induces G1 arrest, endoplasmic reticulum stress, and apoptosis of cancer cell lines.		AChR
T31987	Gossypolone		Wnt/beta-catenin , Gamma-secretase
	Gossypolone is is a proposed major metabolite of gossypol. Gossypolone reduces Notch/Wnt signaling and induces apoptosis.		Wnt/beta-catenin , Gamma-secretase
T61046	Anticancer agent 43		Apoptosis
	Anticancer agent 43 is a potent anticancer agent that induces apoptosis through caspase 3, PARP1, and Bax protein-dependent pathways.Anticancer agent 43 induces DNA damage and can be used in the study of glioblastoma in ...		Apoptosis
T16777	ROC-325		Apoptosis , Autophagy
	ROC-325 is an effective and orally active inhibitor of autophagy with anticancer activity. ROC-325 induces renal cell carcinoma apoptosis and exhibits favorable selectivity.		Apoptosis , Autophagy
T34262	RAPTA-C		Apoptosis
	RAPTA-C induces EAC cell cycle arrest and apoptosis via the mitochondrial and p53-JNK pathways, and can be used in the study of breast and ovarian cancer.		Apoptosis
T4495	DBET1		Epigenetic Reader Domain
	dBET1 is a hybrid molecule that combines (+)-JQ1 and thalidomide. It induces cereblon-dependent BET protein degradation in vitro (EC50: 430 nM) and induces apoptosis.		Epigenetic Reader Domain
T26917	BTT-3033	BTT3033,BTT 3033	Apoptosis , Integrin
	BTT-3033 is an orally active and potent α2β1 (EC50: 130 nM) inhibitor with an EC50 value of 130 nM. BTT-3033 has an affinity for the α2I domain and inhibits platelet binding to collagen I and cell proliferation.BTT-3033 ...		Apoptosis , Integrin
T4818	Thyminose	2-Deoxy-D-ribose,2-Deoxy-D-arabinose,2-Deoxy-D-erythropentose	Others , Endogenous Metabolite
	Thyminose (2-Deoxy-D-arabinose) induces Apoptosis by inhibiting the synthesis and increasing the efflux of glutathione.		Others , Endogenous Metabolite
T6S1435	Notopterol		Apoptosis , Others
	1. Notopterol induces apoptosis and inhibits cell cycle-specific.		Apoptosis , Others